Along with various national projects, Mrs. Bren Simon is dedicated to a variety of international welfare programs. Under her direction, The Melvin and Bren Simon Foundation has donated a substantial amount of resources to the National Democratic Institute, a large portion of which has been allocated to a number of groups that support women's political participation.
Each year, a percentage of that commitment is given to winners of the Madeleine K. Albright Grant. Most recently, this funding was presented to the Women's Discussion Club of Kyrgyzstan. Formed in 2006, this organization was one of the first groups in Kyrgyzstan to bring together women from diverse backgrounds and political parties to defend the rights and interests of women nationwide.
Other programs to which this support was distributed include the NDI Maghreb Youth of Today, Leaders of Tomorrow Program, The International Network of Women in Politics (iKNOW Politics), NDI Bangladesh and the Bangladesh Alliance of Women Leaders, NDI Guatemala and the Political Association of Mayan Women, and the NDI Guidebook to Women's Political Participation.
Another prolific example of Bren Simon's passion for international gender equality and political progress is the indelible impact she has made in La Romana, Dominican Republic. In 1998, Bren Simon joined the Mission International Rescue Foundation, dedicating a tremendous effort to the children and young women of La Romana, with such projects as Centro de Promocion Rural Max Simon and Bren Simon MIR Foundation Girls' Vocational School. Through these organizations, the MIR Foundation provides religious, social, education, and health services to those in this impoverished area.